Valvular heart disease (VHD) occurs when heart valves do not work correctly and are either valvular stenosis (narrowing) or valvular insufficiency (leaking), significantly contributing to the loss of physical function, quality of life and longevity. HVD has been described as “the next cardiac epidemic” by the Global Heart Hub. HVD affects millions worldwide and goes undetected across the United Kingdom. Despite warnings, it will double in prevalence in the coming decades. Listening to the heart can help boost detection rates and ensure timely treatment. However, it is challenging for many general practitioners to diagnose murmurs, and frequent screening is challenging with the increasing number of patients. This project proposes the world-first, flexible, fully integrated multimodal wearable sensor and assess the quality of recorded signals with the long-term vision of facilitating the screening and monitoring the evolution of heart valve conditions. The next step is to build an implantable version if the stakeholders respond positively to the technology.