Titanium implants are widely used in orthopaedic, spinal, and dental surgery but face challenges such as poor biological activity and post-surgical infections. This PhD project aims to develop next-generation, multi-functional titanium implants with integrated antibacterial surfaces, osteogenic textures, and localised drug delivery capabilities.
Using state-of-the-art UV/IR laser micromachining and plasma focused ion beam nano-fabrication, the project will create hierarchical surface textures across meso-, micro-, and nano-scales to enhance cell attachment and osseointegration. Antibacterial silver, with and without a biodegradable carrier, will be incorporated via an innovative in-situ fusion process. Miniaturised, inverse-tapered drug reservoirs will be engineered to enable sustained, local release of therapeutic agents.
The project will also explore additive manufacturing for integrating drug reservoirs directly into implant structures. Extensive material and surface characterisation (e.g. SEM, AFM, XPS, nanoindentation) will ensure functional performance and stability.
